• 45–46 Apostle Paul‘s mission to Cyprus, where he converts proconsul Quintus Sergius Paullus.^[19]

• 49 Paul’s mission to Philippi, Thessalonikiand Veria;^[20][21] Lydia of Thyatira becomes the first convert to Christianity in Europe after hearing Paul’s words in Philippi proclaiming the Gospel of Christ during his second missionary journey.^[22][23]

Icon of Apostle Andrew, considered the founder and first bishop of the Church of Byzantium.

• 50–51 Paul’s mission to Athens,^[24]during his second missionary journey; Metropolis of Corinth founded during Paul’s first mission to Corinth; Paul writes his two Epistles to the Thessalonians, from Corinth.^[20]

• 52–53 Hierotheos the Thesmothete, a member of the Athenian Areopagoswas converted to Christ by the Apostle Paul and became the first Bishop of Athens, later dying a martyr’s death.^[25][26]

• 54 Paul writes his First Epistle to the Corinthians,^[27]during his third missionary journey.

• 55 Paul writes his Second Epistle to the Corinthiansfrom Illyria Graeca.^[27][28]

• 56 Paul revisits Macedonia.^[29]

• 60 Crucifixion of Apostle Andrewthe First-called, in Patras.^{[27][30][31][32]}

• 61 Barnabas, founder of Church of Cyprus, traditionally thought to have been martyred in Salamis;^[27]Paul’s ship lands at Kaloi Limenes (Fair Havens) on the southern coast of Crete, as he was traveling as a prisoner to Rome.^[33]

• 64 Paul ordained the Apostle Titusbishop of Gortyn in Crete, becoming the first Bishop of Crete.^[34][35]

• 95 Apocalypse of Johnwritten on the island of Patmos.^[36]

• 96 Martyrdom of Dionysius the Areopagiteof the Seventy.^[37][38]

• 100 Death of  John the Theologianin Ephesus.^[39]

)

• 100–293 During the 2nd and 3rd centuries, Greece was divided into provinces including Achaea, Macedonia, and Moesia.^{[40][note 7]}

• 120 Martyrdom of Eleutherios and his mother Anthia.^[41]

• 124 Apostles Quadratusand Aristides present Christian apologies to Emperor Hadrian at Athens.^[42]

• 130-140 Aquilacompletes a literal Greek translation of the Old Testament;^{[43][44][note 8][note 9]} death of Apostle Quadratus, of the Seventy.^[47][48]

• 156 Martyrdom of Polycarp of Smyrna.^[49]